Organic Acids
Medchemexpress LLC Kisspeptin 13 TFA | 98.9% | 1626.81 | 1 MG
Kisspeptin 13 TFA is the TFA salt form of Kisspeptin 13 (HY-P3641). It inhibits glucose-induced insulin secretion with an IC50 of 1.2 nM. Kisspeptin 13 TFA activates the hypothalamic-pituitary-adrenal (HPA) axis, causes hyperthermia, motor behavior and anxiety in rats. This compound interacts with α2-adrenergic and 5-HT2 serotonin receptors and exhibits antidepressant efficacy. It is an activator for GPR54 and GnRH receptor, enhancing memory and being useful in Alzheimer's disease research.
- Inhibits glucose-induced insulin secretion (IC50 of 1.2 nM)
- Activates hypothalamic-pituitary-adrenal (HPA) axis
- Causes hyperthermia, motor behavior and anxiety in rats
- Interacts with α2-adrenergic and 5-HT2 serotonin receptors
- Exhibits antidepressant efficacy
- Activator for GPR54 and GnRH receptor
- Enhances memory
- Useful in Alzheimer's disease research
Medchemexpress LLC Glycyl-Exatecan TFA | 1883333-57-0 | 96.9% | 50 MG
Glycyl-Exatecan TFA is a derivative of Exatecan and functions as an anticancer agent. It exhibits significant antitumor activity and can be utilized for research concerning cancers like solid tumors.
- Derivative of Exatecan
- Functions as an anticancer agent
- Exhibits significant antitumor activity
- Utilized in research concerning cancers like solid tumors
Medchemexpress LLC CPN-351 TFA | 912.11 (free base) | 5 MG
CPN-351 TFA, a pentapeptide, acts as a selective antagonist for human NMUR1, demonstrating a pA2 of 7.35. Its antagonistic effect on human NMUR1 is significantly higher, specifically 10 times greater, than its effect on NMUR2. This compound is suitable for application in inflammation research.
- Selective antagonist of human NMUR1.
- Pentapeptide compound.
- Antagonistic effect on human NMUR1 is 10 times higher than on NMUR2.
- Used in the study of inflammation.
Medchemexpress LLC Mazdutide TFA | 2259884-03-0 | 99.7% | 4563.06 | 1 MG
Mazdutide TFA is a long-acting synthetic oxyntomodulin analog. It acts as a co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR). It stimulates insulin secretion from mouse islets and is utilized in studies for obesity and type 2 diabetes (T2D).
- Acts as a co-agonist of GLP-1R and GCGR
- Stimulates insulin secretion from mouse islets
- Used in studies of obesity and type 2 diabetes
- Reduces body weight and physical intake in diabetic mice with diet-induced obesity
Medchemexpress LLC VU0364572 (TFA) | 1240514-89-9 | 99.3% | 487.51 | 25 MG
VU0364572 TFA is an orally active and selective allosteric agonist of the M1 muscarinic receptor with an EC50 of 0.11 μM. It demonstrates neuroprotective potential for preventing memory impairments and reducing neuropathology in Alzheimer's Disease and is CNS penetrant.
- Orally active and selective allosteric agonist of the M1 muscarinic receptor.
- Neuroprotective potential for preventing memory impairments.
- Reduces neuropathology in Alzheimer's Disease.
- CNS penetrant.
Pfaltz & Bauer Trifluoroacetic acid anhydride 100G | 407-25-0
Trifluoroacetic acid anhydride 100G | 407-25-0
Medchemexpress LLC FLAG peptide TFA | 99.6% | 1012.97 (free base) | 25 MG
FLAG peptide TFA is the TFA salt form of FLAG peptide. It is a multifunctional fusion tag used for the purification of recombinant proteins. It maintains the natural folding of its fusing proteins and can be removed by enterokinase, and eluted under non-denaturing conditions.
- Used as a multifunctional fusion tag
- Purifies recombinant proteins
- Maintains natural folding of fusing proteins
- Can be removed by enterokinase
- Eluted under non-denaturing conditions
Apexbio Technology LLC Protease Inhibitor Cocktail for bacterial cell extracts (100 X in DMSO) 10x(1ml A 1ml B)
Under stable environmental conditions endogenous protein synthesis and degradation are balanced thus maintaining stable cellular protein levels Cell crude extracts contain numerous endogenous enzymes such as phosphatases and proteases that can degrade proteins in the extracts During in vitro protein extraction from cells and tissues protein synthesis practically ceases while protein degradation increases The optimal way to enhance yields of intact proteins is to add inhibitors for these known enzymes The Protease Inhibitor Cocktail for bacterial cell extracts (100X in DMSO) is designed for bacterial extracts to enhance the stability of proteins This cocktail inhibits proteases responsible for degrading non-phosphorylated or phosphorylated protein substrates This Protease Inhibitor Cocktail is provided as a ready-to-use solution and it is formulated in DMSO
Medchemexpress LLC GRGDSPC TFA | 99.2% | 804.75 | 5 MG
GRGDSPC TFA is a 7-amino acid thiolated cell adhesion peptide. It is utilized in conjugation reactions with acrylated dextran to regulate the interactions of human mesenchymal stem cells (hMSCs) with photocrosslinkable hydrogels.
- Thiolated cell adhesion peptide
- Composed of 7 amino acids
- Regulates human mesenchymal stem cell interactions
- Suitable for research applications
Medchemexpress LLC FRETS-VWF73 | 97.3% | 8314.28 | 1 MG
FRETS-VWF73 is a 73-amino-acid peptide that serves as a fluorogenic substrate for the ADAMTS13 assay (Ex = 340 nm; Em = 450 nm). It is utilized as a predictive tool for thrombotic thrombocytopenic purpura and is intended for research use only.
- Functions as a fluorogenic substrate for ADAMTS13 assay
- Predictive tool for thrombotic thrombocytopenic purpura
- Excitation wavelength: 340 nm
- Emission wavelength: 450 nm
- Purity: 97.3%
- Molecular weight: 8314.28
- Appearance: Solid, light yellow to yellow
- Solubility: 25 mg/mL in DMSO
Medchemexpress LLC SETD2-IN-1 (TFA) | 2411759-92-5 | 97.2% | 514.51 | 100 MG
EZM0414 TFA is the TFA salt form of EZM0414. It is a potent, selective, and orally active inhibitor of SETD2, with an IC50 of 18 nM in a biochemical assay and 34 nM in a cellular assay. This product is intended for research related to relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma.
- Potent, selective, and orally active inhibitor of SETD2.
- Inhibits proliferation of multiple myeloma and diffuse large B-cell lymphoma cell lines.
- Demonstrated robust tumor growth regressions in xenograft models.
- Correlated with reductions in intratumoral H3K36me3 levels.
- Well-tolerated in animal models.
- Exhibits high oral bioavailability in rats and mice.
eMolecules 76045-93-7 | 2,2,2-Trifluoroacetic acid- 2-bromoethyl ester | Oakwood Chemical | MFCD28396350 | 220.973 | C4H4BrF3O2 | 98.000 | FC(F)(F)C(=O)OCCBr | 1g | 537706582
2,2,2-Trifluoroacetic acid- 2-bromoethyl ester | Oakwood Chemical | 76045-93-7 | MFCD28396350 | 220.973 | C4H4BrF3O2 | 98.000 | FC(F)(F)C(=O)OCCBr | 1g | 537706582
Medchemexpress LLC Relamorelin (TFA) | 2863659-22-5 | 99.8% | 905.00 | 25 MG
Relamorelin TFA is a pentapeptide ghrelin analog and a selective ghrelin/growth hormone secretagogue receptor (GHSR) agonist with a Ki of 0.42 nM for the GHS-1a receptor. It is centrally penetrant, increases growth hormone levels, and accelerates gastric emptying. This compound has potential for research into cachexia, gastroparesis, and gastric/intestinal dysmobility disorders.
- Pentapeptide ghrelin analog
- Selective ghrelin/growth hormone secretagogue receptor (GHSR) agonist
- Ki of 0.42 nM for GHS-1a receptor
- Centrally penetrant
- Increases growth hormone levels
- Accelerates gastric emptying
- Shows ~3 times greater affinity for GHS-1a (Ki=0.42 nM) than native ghrelin (Ki=1.12 nM)
- 6 times more potent (EC50=0.71 nM) in activating the GHS-1a receptor than native ghrelin (EC50=4.2 nM) in vitro by calcium mobilization
- Solid appearance, white to off-white color
- For research use only.
Medchemexpress LLC Bio-AMS TFA | 00-00-0 | 98.0% | 685.65 g/mol | C22H30F3N9O9S2 | 5 MG
Bio-AMS TFA is a bacterial biotin protein ligase inhibitor supplied as the trifluoroacetate (TFA) salt for research use. It shows selective activity against Mycobacterium tuberculosis and disrupts fatty acid and lipid biosynthesis.
- Potent biotin protein ligase inhibition.
- Selective activity against Mycobacterium tuberculosis.
- Provided as the TFA salt to aid handling and solubility.
- High purity: 98.0%.
- Molecular weight 685.65 g/mol; formula C22H30F3N9O9S2.
- Available in small research pack sizes, including 5 mg.
- Suitable for biochemical and microbiology research applications.
Medchemexpress LLC Flonoltinib TFA | 2928093-29-0 | >98.0% | 1 ML
Flonoltinib TFA is a potent and orally active dual JAK2/FLT3 inhibitor with anti-cancer activity, designed for research applications.
- Potent and orally active dual JAK2/FLT3 inhibitor.
- Exhibits anti-cancer activity.
- Down-regulates p-FLT3 in a dose-dependent manner.
- Induces apoptosis and cell cycle arrest in MV4-11 cells.